Difference between revisions of "Services"

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== Services ==
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Due to its ability to accurately identify both arrays of biomolecules, and/or low abundance biomolecules, hybrid mass spectrometry has become recognized as the gold standard for the identification of commercially significant biomarkers. The detection of these biomarkers in samples such as tissues, cells, and a variety of human bodily fluids facilitates the early detection of diseases and helps identifying individualized therapies for patients. As a result, hybrid mass spectrometry, particularly when integrated with bioinformatics tools, is seeing exponential growth in the validation and discovery of biomarkers relevant to disease detection, disease monitoring, drug response and drug safety prediction, and personalized medicine.
 
Due to its ability to accurately identify both arrays of biomolecules, and/or low abundance biomolecules, hybrid mass spectrometry has become recognized as the gold standard for the identification of commercially significant biomarkers. The detection of these biomarkers in samples such as tissues, cells, and a variety of human bodily fluids facilitates the early detection of diseases and helps identifying individualized therapies for patients. As a result, hybrid mass spectrometry, particularly when integrated with bioinformatics tools, is seeing exponential growth in the validation and discovery of biomarkers relevant to disease detection, disease monitoring, drug response and drug safety prediction, and personalized medicine.
  
 
Spectroglyph is committed to providing analytical services at unsurpassed sensitivity and selectivity using state-of-the-art proprietary technologies.
 
Spectroglyph is committed to providing analytical services at unsurpassed sensitivity and selectivity using state-of-the-art proprietary technologies.
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= Products =
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<P></P>
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* <b>[[MALDI/ESI Injector]]</b> - MALDI/ESI Injector has been coupled to and validated with all Thermo's Q Exactive and hybrid Orbitrap models.  Our interface combines orthogonal ESI and front-side illumination MALDI, which could be run simultaneously.  Spectroglyph provides a complete unsurpassed solution for tissue imaging applications.
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<!--* <b>[[Native MS Injector]]</b> - Our Native MS Injector uses the MS^3 approach to discover native protein complexes using a Dual Ion Funnel interface.  Our technique includes combining quadrupole selection with trap/release in order to fragment the native protein complex into sub-units. -->
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* <b>[[IFT Injector]]</b> - A “front end” add-on which drastically lowers the limit of detection and improves desolvation of both intact protein complexes and proteins ionized from highly complex biochemical mixtures.
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* <b>[[Smart MSMS]]</b> - Our Smart MS2 software suite is used to efficiently control hybrid ion trap FTMS instruments manufactured by Thermo Fisher Scientific.
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* <b>[[IMS Orbitrap]]</b> - Our novel IMS instrument coupled to a Thermo Fisher Scientific Q Exactive Orbitrap™ mass spectrometer enables both sequencing and structural characterization of proteins from complex biochemical mixtures.
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<P></P><BR>
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<center>[mailto:info@spectroglyph.com Mail Spectroglyph]</center>
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[[Category:IFT Injector Interface]]
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[[Category:Bottom-up proteomics with HeLa cell digests]]
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[[Category:Increasing Efficiency of Surface Acoustic Wave Nebulization (SAWN) with an Ion Funnel]]
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[[Category:Extending the upper mass limit of Orbitrap Mass Spectrometry]]
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[[Category:From Protein Complexes to Subunit Backbone Fragments:A Multistage Approach to Native MS]]
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[[Category:Multi-step Sequencing and Confident Identification of Native Protein Complexes]]
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[[Category:Bridging the Gap between Ion Mobility Spectrometry and an Orbitrap]]
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[[Category:Triple-Stage Mass Spectrometry Unravels the Heterogeneity of an Endogenous Protein Complex ]]
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[[Category: Design and Performance of a Novel Interface for Combined MALDI and ESI]]
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[[Category: Laser post-ionization combined for enhanced MALDI-MS imaging of lipids]]
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[[Category: Mass spectrometry imaging with isomeric resolution enabled by ozone-induced dissociation]]
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[[Category: Novel Interface for Combined Matrix-Assisted Laser Desorption and Electrospray Ionization]]
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[[Category: Automated, parallel mass spectrometry imaging and structural identification of lipids]]
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[[Category: MALDI/ESI_Injector Data]]
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[[Category: MALDI/ESI Injector User Manual]]

Latest revision as of 10:02, 17 May 2019

Due to its ability to accurately identify both arrays of biomolecules, and/or low abundance biomolecules, hybrid mass spectrometry has become recognized as the gold standard for the identification of commercially significant biomarkers. The detection of these biomarkers in samples such as tissues, cells, and a variety of human bodily fluids facilitates the early detection of diseases and helps identifying individualized therapies for patients. As a result, hybrid mass spectrometry, particularly when integrated with bioinformatics tools, is seeing exponential growth in the validation and discovery of biomarkers relevant to disease detection, disease monitoring, drug response and drug safety prediction, and personalized medicine.

Spectroglyph is committed to providing analytical services at unsurpassed sensitivity and selectivity using state-of-the-art proprietary technologies.

Products

  • MALDI/ESI Injector - MALDI/ESI Injector has been coupled to and validated with all Thermo's Q Exactive and hybrid Orbitrap models. Our interface combines orthogonal ESI and front-side illumination MALDI, which could be run simultaneously. Spectroglyph provides a complete unsurpassed solution for tissue imaging applications.
  • IFT Injector - A “front end” add-on which drastically lowers the limit of detection and improves desolvation of both intact protein complexes and proteins ionized from highly complex biochemical mixtures.
  • Smart MSMS - Our Smart MS2 software suite is used to efficiently control hybrid ion trap FTMS instruments manufactured by Thermo Fisher Scientific.
  • IMS Orbitrap - Our novel IMS instrument coupled to a Thermo Fisher Scientific Q Exactive Orbitrap™ mass spectrometer enables both sequencing and structural characterization of proteins from complex biochemical mixtures.


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